Advancing our innovative pipeline
to address unmet needs

Selected Publications

> TransCon Growth Hormone
> TransCon PTH
> TransCon CNP

 

TransCon Growth Hormone

Design and Clinical Development of TransCon Growth Hormone for Growth Hormone Deficiency
M.Beckert, J.M. Mikkelsen, G.N. Rasmussen, H. Rau, K. Sprogoe, J.A. Leff. Poster presented at The Endocrine Society (ENDO) Annual Meeting and Expo, April 1-4, 2017 (Orlando, Fl).

User Driven Development of a New Device for Weekly Growth Hormone Administration in Pediatric Patients
S. Jensen, H. Egesborg, P.E. Fabricius, B. Sørensen, S.V. Jacobsen. Poster presented at The Endocrine Society (ENDO) Annual Meeting and Expo, April 1-4, 2017 (Orlando, Fl).

Design of a Bracketed Dosing Regimen for the Administration of TransCon GH, a Once-Weekly Growth Hormone Product
K. Sprogoe, S. Jensen, H. Egesborg. Poster presented at The Endocrine Society (ENDO) Annual Meeting and Expo, April 1-4, 2017 (Orlando, Fl).

Design and Rationale for the Height Trial, a Phase 3 TransCon GH Study in Children with Growth Hormone Deficiency
M. Beckert, D.B. Karpf, E. Mortensen, J. Mardell, E.D. Christoffersen, J.A. Leff. Poster presented at The Endocrine Society (ENDO) Annual Meeting and Expo, April 1-4, 2017 (Orlando, Fl).

A Randomized Phase 2 Study of Long-Acting TransCon Growth Hormone vs. Daily GH in Childhood GH Deficiency
P. Chatelain, O. Malievsky, K. Radziuk, G. Senatorova, M. Abdou, E. Vlachopapadopolou, Y. Skorodok, V. Peterkova, J. Leff, M. Beckert, the TransCon GH Working Group. JCEM. 2017. jc.2016-3776. doi: 10.1210/jc.2016-3776.

A Phase 2 Trial of Long-acting TransCon Growth Hormone in Adult GH Deficiency
C. Höybye, A. Pfeiffer, D. Ferone, J. Christiansen, D. Gilfoyle, E. Christoffersen, E. Mortensen, J. Leff and M. Beckert. Endocr Connect. 2017. EC-17-0007.

Pediatric Phase 2 Data Demonstrate That TransCon hGH Has an Anti-hGH Immunogenic Profile That Is Comparable to Daily hGH
D. Gilfoyle, S. Pihl, P. Chatelain, M. Beckert. Poster presented at 55th Annual Meeting of the European Society for Paediatric Endocrinology (ESPE), September 10-12, 2016 (Paris, France).

A Six-Month Safety and Efficacy Study of TransCon hGH Compared to Daily hGH in Prepubertal Children with Growth Hormone Deficiency (GHD)
P. Chatelain, O. Malievsky, K. Radziuk, G. Senatorova, M. Beckert. Poster presented at 55th Annual Meeting of the European Society for Paediatric Endocrinology (ESPE), September 10-12, 2016 (Paris, France).

Design and Clinical Development of TransCon Growth Hormone for Growth Hormone Deficiency
M. Beckert, D. Gilfoyle, J.M. Mikkelsen, et al. Poster presented at 55th Annual Meeting of the European Society for Paediatric Endocrinology (ESPE), September 10-12, 2016 (Paris, France).

Pharmacokinetic Modelling Predicts Native hGH Levels Following Administration of a Sustained-release Prodrug, TransCon hGH, to Children With GHD
K. Sprogøe, M. Beckert, E.D. Christoffersen, D. Gilfoyle, T. Wegge. Poster presented at 55th Annual Meeting of the European Society for Paediatric Endocrinology (ESPE), September 10-12, 2016 (Paris, France).

TransCon PTH

TransCon PTH, a Sustained Release PTH Analogue for the Treatment of Hypoparathyroidism – Proof-of-Principle in Monkeys and Tptx Rats
K.Sprogoe, L. Holten-Andersen, F. Cleeman, J. Zettler, S. Pihl, V.M. Breinholt. Poster presented at The Endocrine Society (ENDO) Annual Meeting and Expo, April 1-4, 2017 (Orlando, Fl).

Pharmacokinetics of TransCon PTH, a Sustained-Release PTH Prodrug for Hypoparathyroidism, in Rat and Cynomolgus Monkey
K. Sprogoe, S. Pihl, C.E. Rasmussen, L. Holten-Andersen, F. Cleeman, V.M. Breinholt. Poster presented at The Endocrine Society (ENDO) Annual Meeting and Expo, April 1-4, 2017 (Orlando, Fl).

TransCon CNP

TransCon CNP, a Sustained-Release Prodrug of C-Type Natriuretic Peptide, Effects Positive Bone Growth in Young Cynomolgus Monkeys and in a Mouse Model of Achondroplasia
V.M. Breinholt, N.Kaci, C.E. Rasmussen, O. Keil, S. Adermann, U. Hersel, M. Cornille, P. H. Mygind, K. Sprogoe, L. Legeai-Mallet. Poster presented at The Endocrine Society (ENDO) Annual Meeting and Expo, April 1-4, 2017 (Orlando, Fl).

TransCon CNP, a Sustained-Release C-Type Natriuretic Peptide Analogue, for the Treatment of Achondroplasia
K. Sprogoe, C.E. Rasmussen, U. Hersel, V.M. Breinholt. Poster presented at The Endocrine Society (ENDO) Annual Meeting and Expo, April 1-4, 2017 (Orlando, Fl).

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